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  GenStat  ~  REML meta-analysis

Kirsty Hassall
Posted: Fri Mar 15, 2019 8:59 am Reply with quote
Dear Genstatters,

I am attempting to fit a meta-analysis across 8 different field experiments, each of which has a separate residual structure. The commands to set this up are:

vrmeta [terms=Environment*Genotype; experiments=Environment; random=random] \
!f(block/subblock),!f(block/subblock),!f(block/subblock), \
!f(block/(row12F + col12F)), !f(block)
vcomp [Genotype; Experiments=Environment] #random
vresid [experiment='2008R'; term=row08rF.col08rF] model=ar,ar; factor=row08rF,col08rF
vresid [experiment='2010'; term=row10F.col10F] model=ar,ar; factor=row10F,col10F
vresid [experiment='2011'; term=row11F.col11F] model=AR; order=1; factor=col11F
vresid [experiment='2012'; term=block.row12F.col12F] model=AR; order=1; factor=col12F
vresid [experiment='2014'; term=row14F.col14F] model=AR; order=1; factor=col14F
reml [mvincl=y,e; work=500] GY

Running the above, produces output for the random effects and residual terms which all seem to match the structure I would expect (i.e. no additional residual terms are added etc…). However, before reaching the output for the fixed effects I have the error “Genstat server applictaion has stopped working: A problem caused the program to stop working”.

Any advice on how to cope with this error would be greatly appreciated. Note, the above works if I remove the spatial structure over the residuals.

Thanks in advance,

Dr Kirsty Hassall
Scientific Statistician

Department of Computational and Analytical Sciences
Rothamsted Research
Harpenden, Herts

Tel: +44(0) 1582 763133 Ext: 2080
Email: kirsty.hassall@rothamsted.ac.uk (kirsty.hassall@rothamsted.ac.uk)

Rothamsted Research is a company limited by guarantee, registered in England at Harpenden, Hertfordshire, AL5 2JQ under the registration number 2393175 and a not for profit charity number 802038.

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